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Interleukin-1-induced nonspecific resistance to bacterial infection in mice is not mediated by glucocorticosteroids.

Preexposure to a low dose of interleukin-1 (IL-1; 3 to 30 micrograms/kg) 24 h before a lethal gram-negative bacterial infection prolonged survival in normal and granulocytopenic mice. To examine whether this protective effect is mediated by glucocorticosteroids, we first measured corticosterone conc...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Vogels, M T, Sweep, C G, Hermus, A R, van der Meer, J W
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1482145/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2785
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