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In vitro pharmacodynamic effects of concentration, pH, and growth phase on serum bactericidal activities of daptomycin and vancomycin.

Clinical trials with daptomycin were halted in December 1990 because of treatment failures including two resistant Staphylococcus aureus strains. High protein binding of daptomycin (> 90%) and the lower-than-expected concentrations in serum with the dosage regimen of 3 mg/kg of body weight every 12...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lamp, K C, Rybak, M J, Bailey, E M, Kaatz, G W
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245533/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336344/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2709
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