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In vivo efficacy of a new fluoroquinolone, sparfloxacin, against penicillin-susceptible and -resistant and multiresistant strains of Streptococcus pneumoniae in a mouse model of pneumonia.

The increasing emergence of penicillin-resistant and multiresistant strains of Streptococcus pneumoniae may pose a problem in coming years. We therefore compared sparfloxacin, a new fluoroquinolone with improved potency against streptococci, with amoxicillin, the "gold standard" in this setting, and...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Azoulay-Dupuis, E, Vallee, E, Veber, B, Bedos, J P, Bauchet, J, Pocidalo, J J
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245531/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1336343/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2698
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