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Pharmacokinetics and transplacental passage of imipenem during pregnancy.

Imipenem pharmacokinetics were studied in early pregnancy (n = 7; length of gestation, 8.6 +/- 1.5 weeks, mean +/- standard deviation), in late pregnancy (n = 7; length of gestation, 38.7 +/- 1.4 weeks), and in the nonpregnant state (n = 6). A single dose of 500 mg of imipenem-cilastatin (1:1) was a...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Heikkilä, A, Renkonen, O V, Erkkola, R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1482132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.12.2652
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