Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography.

18F-labeled fleroxacin was used to measure the pharmacokinetics of fleroxacin in healthy and infected animals by positron emission tomography (PET) and tissue radioactivity measurements. In all experiments, a pharmacological dose of unlabeled drug (10 mg/kg) was coinjected with the tracer. The pharm...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Fischman, A J, Livni, E, Babich, J, Alpert, N M, Liu, Y Y, Thom, E, Cleeland, R, Prosser, B L, Callahan, R J, Correia, J A
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245491/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1444310/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.10.2286
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