Pharmacokinetics of 18F-labeled fleroxacin in rabbits with Escherichia coli infections, studied with positron emission tomography.

18F-labeled fleroxacin was used to measure the pharmacokinetics of fleroxacin in healthy and infected animals by positron emission tomography (PET) and tissue radioactivity measurements. In all experiments, a pharmacological dose of unlabeled drug (10 mg/kg) was coinjected with the tracer. The pharm...

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Bibliographic Details
Main Authors: Fischman, A J, Livni, E, Babich, J, Alpert, N M, Liu, Y Y, Thom, E, Cleeland, R, Prosser, B L, Callahan, R J, Correia, J A
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC245491/
https://ncbi.nlm.nih.gov/pubmed/1444310
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