In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen

T cells recognizing poorly displayed self determinants escape tolerance mechanisms and persist in the adult repertoire. The process by which these T cells are primed is not clear, but once activated, they can cause autoimmunity. Here, we show that dendritic cells treated with interleukin 6 (IL-6) pr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Drakesmith, Hal, O’Neil, Deborah, Schneider, Susanne C., Binks, Mike, Medd, Patrick, Sercarz, Eli, Beverley, Peter, Chain, Benjamin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9843988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.25.14903
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