Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery.

Candida albicans is an opportunistic pathogen responsible for life-threatening infections in persons with impaired immune systems. Topoisomerase I is a potential target for novel antifungal agents; however, in order for this enzyme to be a therapeutically useful target, it needs to be demonstrated t...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Fostel, J M, Montgomery, D A, Shen, L L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1332588/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.10.2131
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