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Mannose-binding lectin deficiency is associated with early onset of polyarticular juvenile rheumatoid arthritis: a cohort study

BACKGROUND: Mannose-binding lectin (MBL) is an innate immune protein. The aim of our study was to determine whether genetically determined MBL deficiency is associated with susceptibility to juvenile rheumatoid arthritis (JRA) and whether MBL2 genotypes are associated with JRA severity. METHODS: In...

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Auteurs principaux: Dolman, Koert M, Brouwer, Nannette, Frakking, Florine NJ, Flatø, Berit, Tak, Paul P, Kuijpers, Taco W, Førre, Øystein, Smerdel-Ramoya, Anna
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453777/
https://ncbi.nlm.nih.gov/pubmed/18334024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2386
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