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Mucosal administration of α-fodrin inhibits experimental Sjögren's syndrome autoimmunity

INTRODUCTION: α-Fodrin is an autoantigen in Sjögren's syndrome. We hypothesized that mucosal administration of α-fodrin might prevent the disease. METHODS: Four-week-old NOD mice were immunized (intranasal) with a 1 μg or 10 μg dose of α-fodrin every other day. PBS 10 μl/dose and Glutathione tr...

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Bibliographische Detailangaben
Hauptverfasser: He, Jing, Zhao, Jinxia, Li, Zhanguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453764/
https://ncbi.nlm.nih.gov/pubmed/18419828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2403
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