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Essential role of platelet activation via protease activated receptor 4 in tissue factor-initiated inflammation

INTRODUCTION: Tissue factor (TF) activation of the coagulation proteases enhances inflammation in animal models of arthritis and endotoxemia, but the mechanism of this effect is not yet fully understood – in particular, whether this is primarily due to fibrin formation or through activation of prote...

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Detalhes bibliográficos
Main Authors: Busso, Nathalie, Chobaz-Péclat, Veronique, Hamilton, Justin, Spee, Pieter, Wagtmann, Nicolai, So, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453761/
https://ncbi.nlm.nih.gov/pubmed/18412955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2400
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