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Numbers needed to treat calculated from responder rates give a better indication of efficacy in osteoarthritis trials than mean pain scores

INTRODUCTION: Osteoarthritis trials usually report average changes in visual analogue scale (VAS) pain, and examine the difference between treatment and placebo. We investigated whether dichotomous responder analysis provides a more informative interpretation of drug efficacy. METHODS: Merck supplie...

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Библиографические подробности
Главные авторы: Moore, R Andrew, Moore, Owen A, Derry, Sheena, McQuay, Henry J
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453757/
https://ncbi.nlm.nih.gov/pubmed/18384679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2394
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