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Daptomycin disrupts membrane potential in growing Staphylococcus aureus.

Daptomycin (LY146032) caused a calcium-dependent dissipation of the membrane potential (delta psi) in Staphylococcus aureus without noticeably affecting the chemical gradient (delta pH) across the membrane. The effect of daptomycin on membrane energization may account for many of the inhibitory effe...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Alborn, W E, Allen, N E, Preston, D A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1666494/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.11.2282
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