Pharmacokinetics of ceftibuten-cis and its trans metabolite in healthy volunteers and in patients with chronic renal insufficiency.

The impact of renal insufficiency on the dispositions of 300 mg of orally administered ceftibuten-cis, a new broad-spectrum oral cephalosporin, and its primary metabolite ceftibuten-trans was characterized in 30 adult subjects. Subjects were divided into five groups of six subjects each on the basis...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Kelloway, J S, Awni, W M, Lin, C C, Lim, J, Affrime, M B, Keane, W F, Matzke, G R, Halstenson, C E
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245370/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1803999/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.11.2267
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