Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo.

Two antiviral compounds, (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine [DHPG], were evaluated for their inhibitory effects on human cytomegalovirus (HCMV) replication in human embryonal fibroblasts and on rat cytomegalovirus (RCMV) replicati...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Stals, F S, de Clercq, E, Bruggeman, C A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1666493/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.11.2262
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