Plasma C5 Glucose–to–(2)H(2)O Ratio Does Not Provide an Accurate Assessment of Gluconeogenesis During Hyperinsulinemic-Euglycemic Clamps in Either Nondiabetic or Diabetic Humans

OBJECTIVE—Measurement of plasma C2 glucose enrichment is cumbersome. Therefore, the plasma C5 glucose–to–(2)H(2)O rather than the plasma C5-to-C2 glucose ratio commonly has been used to measure gluconeogenesis and glycogenolysis during hyperinsulinemic-euglycemic clamps. The validity of this approac...

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Bibliographic Details
Main Authors: Basu, Rita, Chandramouli, Visvanathan, Dicke, Betty, Landau, Bernard R., Rizza, Robert A.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2008
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453627/
https://ncbi.nlm.nih.gov/pubmed/18420484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0195
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