Blockade of α4 Integrin Signaling Ameliorates the Metabolic Consequences of High-Fat Diet–Induced Obesity

OBJECTIVE—Many prevalent diseases of advanced societies, such as obesity-induced type 2 diabetes, are linked to indolent mononuclear cell–dependent inflammation. We previously proposed that blockade of α4 integrin signaling can inhibit inflammation while limiting mechanism-based toxicities of loss o...

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Detalles Bibliográficos
Main Authors: Féral, Chloé C., Neels, Jaap G., Kummer, Christiane, Slepak, Marina, Olefsky, Jerrold M., Ginsberg, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2008
Assuntos:
Obesity Studies
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453617/
https://ncbi.nlm.nih.gov/pubmed/18426864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1751
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