Antiviral and pharmacokinetic properties of C2 symmetric inhibitors of the human immunodeficiency virus type 1 protease.

Specific processing of the human immunodeficiency virus (HIV) gag and gag-pol polyprotein gene products by the HIV protease is essential for the production of mature, infections progeny virions. Inhibitors of HIV protease block this maturation and thus prohibit the spread of HIV in vitro. Previously...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kempf, D J, Marsh, K C, Paul, D A, Knigge, M F, Norbeck, D W, Kohlbrenner, W E, Codacovi, L, Vasavanonda, S, Bryant, P, Wang, X C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1803993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.11.2209
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