Increased resistance to multiple drugs by introduction of the Enterobacter cloacae romA gene into OmpF porin-deficient mutants of Escherichia coli K-12.

Introduction of the romA gene cloned from Enterobacter cloacae into Escherichia coli K-12 resulted in almost complete inhibition of OmpF expression and a concomitant increase in resistance to quinolones, beta-lactams, chloramphenicol, and tetracyclines. In addition, the romA gene reduced the suscept...

Full description

Saved in:
Bibliographic Details
Main Authors: Komatsu, T, Ohta, M, Kido, N, Arakawa, Y, Ito, H, Kato, N
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC245346/
https://ncbi.nlm.nih.gov/pubmed/1662028
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items