Role of protein D2 and lipopolysaccharide in diffusion of quinolones through the outer membrane of Pseudomonas aeruginosa.

Routes of quinolone permeation in Pseudomonas aeruginosa were investigated by using sparfloxacin as a prototype compound. [14C]sparfloxacin cell labeling was 13 to 28% lower in three protein D2-deficient mutants resistant to imipenem than in their imipenem-susceptible counterparts. In four impermeab...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Michéa-Hamzehpour, M, Furet, Y X, Pechère, J C
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1662023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.10.2091
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