Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus

Recent studies in animal models for systemic lupus erythematosus (SLE) have shown that Toll-like receptors (TLR-7 and TLR-9) and interferon (IFN)-α are involved in the pathogenesis of murine lupus. Recent studies using flow cytometry have also shown increased expression of TLR-9 in peripheral blood...

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Autors principals: Komatsuda, A, Wakui, H, Iwamoto, K, Ozawa, M, Togashi, M, Masai, R, Maki, N, Hatakeyama, T, Sawada, K
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2008
Matèries:
Translational Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453201/
https://ncbi.nlm.nih.gov/pubmed/18373699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2008.03646.x
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