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A Novel Role of the NRF2 Transcription Factor in the Regulation of Arsenite-Mediated Keratin 16 Gene Expression in Human Keratinocytes

BACKGROUND: Inorganic sodium arsenite (iAs) is a ubiquitous environmental contaminant and is associated with an increased risk of skin hyperkeratosis and cancer. OBJECTIVES: We investigated the molecular mechanisms underlying the regulation of the keratin 16 (K16) gene by iAs in the human keratinocy...

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Bibliographische Detailangaben
Hauptverfasser: Endo, Hitoshi, Sugioka, Yoshihiko, Nakagi, Yoshihiko, Saijo, Yasuaki, Yoshida, Takahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Institute of Environmental Health Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453154/
https://ncbi.nlm.nih.gov/pubmed/18629308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.10696
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