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Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by two-drug and three-drug combinations of 3'-azido-3'-deoxythymidine, phosphonoformate, and 2',3'-dideoxythymidine.

The effects of 3'-azido-3'-deoxythymidine (AZT), phosphonoformate (PFA), and 2',3'-dideoxythymidine (ddT) and their combination on human immunodeficiency type 1 (HIV-1) replication were studied by measuring the HIV-1 p24 antigen expression and reverse transcriptase (RT) release in HIV-1-infected MT4...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Kong, X B, Zhu, Q Y, Ruprecht, R M, Watanabe, K A, Zeidler, J M, Gold, J W, Polsky, B, Armstrong, D, Chou, T C
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245315/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1722077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.10.2003
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