Cultured Murine Thyroid Epithelial Cells Expressing Transgenic Fas-Associated Death Domain-Like Interleukin-1β Converting Enzyme Inhibitory Protein Are Protected from Fas-Mediated Apoptosis

The antiapoptotic molecule Fas-associated death domain-like IL-1β-converting enzyme inhibitory protein (FLIP) inhibits Fas-mediated apoptosis by blocking activation of caspase-8. We previously showed that expression of transgenic FLIP on thyroid epithelial cells (TECs) of DBA/1 and CBA/J mice promot...

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Bibliographic Details
Main Authors: Fang, Yujiang, Braley-Mullen, Helen
Format: Artigo
Language:Inglês
Published: The Endocrine Society 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453085/
https://ncbi.nlm.nih.gov/pubmed/18356280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0080
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