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Cyclic Adenosine 3′,5′-Monophosphate Responsive Element Binding Protein Phosphorylation Is Required But Not Sufficient for Activation of Corticotropin-Releasing Hormone Transcription

cAMP is a major regulator of CRH transcription. However, receptors activating CRH neurons (α-adrenergic and glutamatergic) do not signal through cAMP, suggesting that calcium phospholipid-dependent signaling synergizes with small elevations of intracellular cAMP. To test this hypothesis, we examined...

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Detalles Bibliográficos
Main Authors: Liu, Ying, Kamitakahara, Anna, Kim, Alice Joohee, Aguilera, Greti
Formato: Artigo
Idioma:Inglês
Publicado: The Endocrine Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453084/
https://ncbi.nlm.nih.gov/pubmed/18372325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0052
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