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Estrogen Inhibits Cardiac Hypertrophy: Role of Estrogen Receptor-β to Inhibit Calcineurin

Estrogen has been reported to prevent development of cardiac hypertrophy in female rodent models and in humans. However, the mechanisms of sex steroid action are incompletely understood. We determined the cellular effects by which 17β-estradiol (E2) inhibits angiotensin II (AngII)-induced cardiac hy...

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Main Authors: Pedram, Ali, Razandi, Mahnaz, Lubahn, Dennis, Liu, Jinghua, Vannan, Mani, Levin, Ellis R.
Formato: Artigo
Idioma:Inglês
Publicado: The Endocrine Society 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453079/
https://ncbi.nlm.nih.gov/pubmed/18372323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0133
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