Leptin Does Not Mediate Short-Term Fasting-Induced Changes in Growth Hormone Pulsatility but Increases IGF-I in Leptin Deficiency States

Context: States of acute and chronic energy deficit are characterized by increased GH secretion and decreased IGF-I levels. Objective: The objective of the study was to determine whether changes in levels of leptin, a key mediator of the adaptation to starvation, regulate the GH-IGF system during en...

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Autori principali: Chan, Jean L., Williams, Catherine J., Raciti, Patricia, Blakeman, Jennifer, Kelesidis, Theodore, Kelesidis, Iosif, Johnson, Michael L., Thorner, Michael O., Mantzoros, Christos S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453057/
https://ncbi.nlm.nih.gov/pubmed/18445667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-0056
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