Infliximab and Etanercept Are Equally Effective in Reducing Enterocyte APOPTOSIS in Experimental Colitis

Loss of epithelial barrier integrity is considered an early step in the pathogenesis of Crohn's disease (CD), and the rate of enterocyte apoptosis is one of the determinants of the intestinal barrier function. Tumor necrosis factor-α (TNF-α), one of the major proinflammatory mediators in CD, is...

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Bibliographic Details
Main Authors: Fries, Walter, Muja, Carmelo, Crisafulli, Carmela, Costantino, Giuseppe, Longo, Giuseppe, Cuzzocrea, Salvatore, Mazzon, Emanuela
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2008
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2452978/
https://ncbi.nlm.nih.gov/pubmed/18645606
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