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Appearance of a new trimethoprim resistance gene, dhfrIX, in Escherichia coli from swine.

A new gene, dhfrIX, coding for a trimethoprim-resistant dihydrofolate reductase (DHFR), was found in porcine isolates of Escherichia coli. The new enzyme, DHFR IX, containing 178 amino acids, showed an amino acid similarity of about 26% with DHFR I and the chromosomal DHFR of E. coli K-12. The dhfrI...

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Bibliographic Details
Main Authors: Jansson, C, Sköld, O
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC245287/
https://ncbi.nlm.nih.gov/pubmed/1659308
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