Pharmacokinetics of cefotaxime and its active metabolite in children with renal dysfunction.

We studied cefotaxime (CTX) and desacetylcefotaxime (dCTX) pharmacokinetics in 19 children (ages, 7 to 16 years) with various degrees of renal function. The patients were stratified into three groups according to 24-h urinary creatinine clearance (CLCR) values: group I, CLCR greater than 80 ml/min/1...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Paap, C M, Nahata, M C, Mentser, M A, Mahan, J D, Puri, S K, Hubbard, J W
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1991
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1952862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.9.1879
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