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Effect of pH on the in vitro potency of clarithromycin against Mycobacterium avium complex.

Employing 7H11 agar medium at pH 6.6, the MICs of clarithromycin for 50% (MIC50) and 90% (MIC90) of 19 strains of Mycobacterium avium complex were 8 and 16 micrograms/ml, respectively. However, the MICs were 2 to 3 log2 dilutions lower in the 7H11 medium adjusted to pH 7.4, and the MICs on 10% OADC...

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Detalhes bibliográficos
Main Authors: Truffot-Pernot, C, Ji, B, Grosset, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC245242/
https://ncbi.nlm.nih.gov/pubmed/1834015
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