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SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor β

The human type VII collagen gene (COL7A1) recently has been identified as an immediate-early response gene for transforming growth factor β (TGF-β)/SMAD signaling pathway. In this study, by using MDA-MB-468 SMAD4−/− breast carcinoma cells, we demonstrate that expression of SMAD4 is an absolute requi...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Vindevoghel, Laurence, Lechleider, Robert J., Kon, Atsushi, de Caestecker, Mark P., Uitto, Jouni, Roberts, Anita B., Mauviel, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24524/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9843964/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.25.14769
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