Treatment of experimental cryptococcosis with SCH 39304 and fluconazole.

The efficacy of two triazoles, SCH 39304 and fluconazole, in the treatment of disseminated cryptococcosis in Wistar rats was determined. A total of 160 rats were inoculated intracardiacally with 2 x 10(5) cells of Cryptococcus neoformans. Both drugs were administered by gavage once daily, at three d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Negroni, R, Costa, M R, Finquelievich, J L, Iovannitti, C, Agorio, I, Tiraboschi, I N, Loebenberg, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1991
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245190/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929309/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1460
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