6-N-substituted derivatives of adenine arabinoside as selective inhibitors of varicella-zoster virus.

A series of 6-alkylaminopurine arabinosides were synthesized and found to inhibit varicella-zoster virus (VZV). The antiviral activities of these nucleosides were limited to VZV. None of the other viruses tested in the herpesvirus family were affected. The in vitro antiviral potencies of the 18 arab...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Koszalka, G W, Averett, D R, Fyfe, J A, Roberts, G B, Spector, T, Biron, K, Krenitsky, T A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1437
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