Correlation between in vitro and in vivo activity of antimicrobial agents against gram-negative bacilli in a murine infection model.

We studied the relationship between in vitro susceptibility tests (MICs, MBCs) and in vivo activity of tobramycin, pefloxacin, ceftazidime, and imipenem against 15 gram-negative bacilli from five different species in a murine thigh infection model. Complete dose-response curves were determined for e...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Fantin, B, Leggett, J, Ebert, S, Craig, W A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245182/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929302/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1413
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