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Efficacy of cilofungin alone and in combination with amphotericin B in a murine model of disseminated aspergillosis.

Cilofungin, amphotericin B, and a combination of the two drugs were compared in a model of aspergillosis in immunocompetent mice in three experiments. Cilofungin was equivalent to amphotericin B in preventing death and eradicating cerebral aspergillosis, but it did not sterilize the kidneys. This is...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Denning, D W, Stevens, D A
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245166/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1929289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1329
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