Interaction of aminoglycosides with the outer membranes and purified lipopolysaccharide and OmpF porin of Escherichia coli.

The mechanism of uptake of aminoglycosides across the outer membrane of Escherichia coli was reevaluated. Porin-deficient mutants showed no alteration in gentamicin or kanamycin susceptibility. Furthermore, the influence of kanamycin on intrinsic tryptophan fluorescence of porin OmpF (Y. Kobayashi,...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Hancock, R E, Farmer, S W, Li, Z S, Poole, K
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656859/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.7.1309
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