In vitro activity and in vivo efficacy of a new series of 9-deoxo-12-deoxy-9,12-epoxyerythromycin A derivatives.

Analogs of 9-deoxo-12-deoxy-9,12-epoxyerythromycin A with an epimeric hydroxy, amino, or ketone substitution at the 11 position of the macrolide ring and an amino or epimeric hydroxy substitution at the 4" position of the cladinose sugar were synthesized in an attempt to produce acid-stable derivati...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Hardy, D J, Swanson, R N, Shipkowitz, N L, Freiberg, L A, Lartey, P A, Clement, J J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245130/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1854173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.922
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