Escherichia coli resistant to cephalosporins and quinolones is still susceptible to the cephalosporin-quinolone ester Ro 23-9424.

Ro 23-9424 is a broad-spectrum antibacterial agent consisting of a cephalosporin (desacetylcefotaxime) linked through an ester bond to a fluoroquinolone (fleroxacin). Its activity against mutants of Escherichia coli TE18 resistant to both antibacterial components was examined. E. coli TE18 overprodu...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Pace, J, Bertasso, A, Georgopapadakou, N H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245128/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1649574/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.910
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