Comparative efficacies of ciprofloxacin, amoxicillin, amoxicillin-clavulanic acid, and cefaclor against experimental Streptococcus pneumoniae respiratory infections in mice.

Experimental respiratory infections were established in mice by intranasal inoculation of Streptococcus pneumoniae. Inoculation of 10(7) CFU of either S. pneumoniae 1629 or S. pneumoniae 7 produced a fatal pneumonia in nontreated mice 2 to 3 days after infection. Oral therapy was commenced 1 h after...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Gisby, J, Wightman, B J, Beale, A S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245115/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1854164/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.5.831
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