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A cholecystokinin-1 receptor agonist (CCK-8) mediates increased permeability of brain barriers to leptin

BACKGROUND AND PURPOSE: Leptin regulates energy expenditure and body weight by acting both on the hypothalamus and on peripheral targets. Central actions of leptin are enhanced by cholecystokinin (CCK). The interaction between leptin and CCK makes physiological sense, as rats lacking CCK(1) receptor...

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Main Authors: Cano, V, Merino, B, Ezquerra, L, Somoza, B, Ruiz-Gayo, M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2451056/
https://ncbi.nlm.nih.gov/pubmed/18587446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.149
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