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Pharmacokinetics of 2',3'-dideoxyinosine (BMY-40900), a new anti-human immunodeficiency virus agent, after administration of single intravenous doses to beagle dogs.

The pharmacokinetics of 2',3'-dideoxyinosine (ddI) were investigated in four adult male beagle dogs that received 15-min infusions of 20-, 50-, and 100-mg/kg doses in a randomized crossover study design. Plasma and urine samples were collected for 10 and 24 h, respectively, and assayed for ddI by hi...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Kaul, S, Knupp, C A, Dandekar, K A, Pittman, K A, Barbhaiya, R H
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1991
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245067/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1906259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.4.610
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