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Once-daily aminoglycoside therapy.

The once-daily administration of aminoglycosides is an attractive concept. In animal experiments and clinical trials, there is either a reduction in or no influence on the risk of toxicity. Less frequent dosing reduces the contact time between host tissue binding sites and drug. Thanks to the PAE an...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Autor principal: Gilbert, D N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2039189/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.3.399
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