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Penetration of ofloxacin into human lung tissue following a single oral dose of 200 milligrams.

The penetration of ofloxacin into lung tissue was studied in 10 patients subjected to pulmonary surgery. Samples of blood and lung tissue were obtained 3 to 8 h (mean, 5 h) after oral administration of 200 mg. The mean level in tissue was 2.17 +/- 0.5 micrograms/g, while the mean level in serum was...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Serour, F, Dan, M, Gorea, A, Yellin, A, Lieberman, Y, Berger, S A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC245011/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2024972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.2.380
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