Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

To create a universal system for the control of gene expression, we have studied methods for the construction of novel polydactyl zinc finger proteins that recognize extended DNA sequences. Elsewhere we have described the generation of zinc finger domains recognizing sequences of the 5′-GNN-3′ subse...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Beerli, Roger R., Segal, David J., Dreier, Birgit, Barbas, Carlos F.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1998
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24500/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9843940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.25.14628
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