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Penicillin-resistant isolates of Neisseria lactamica produce altered forms of penicillin-binding protein 2 that arose by interspecies horizontal gene transfer.

Isolates of Neisseria lactamica that have increased resistance to penicillin have emerged in recent years. Resistance to penicillin was shown to be due to the production of altered forms of penicillin-binding protein 2 (PBP 2) that have reduced affinity for the antibiotic. The sequences of the PBP 2...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Lujan, R, Zhang, Q Y, Sáez Nieto, J A, Jones, D M, Spratt, B G
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2024965/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.2.300
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