Remarkable in vitro and in vivo activities of the hydroxynaphthoquinone 566C80 against tachyzoites and tissue cysts of Toxoplasma gondii.

Compound 566C80, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone, was studied for its in vitro and in vivo activities against Toxoplasma gondii. Replication within human foreskin fibroblasts of tachyzoites of seven different strains, five of them isolated from AIDS patients, was...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Araujo, F G, Huskinson, J, Remington, J S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2024964/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.2.293
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