8-Aminoquinolines from Walter Reed Army Institute for Research for treatment and prophylaxis of Pneumocystis pneumonia in rat models.

Three 8-aminoquinolines from the Walter Reed Army Institute for Research (WRAIR), WR6026, WR238605, and WR242511, strongly inhibited Pneumocystis carinii growth in vitro at 1 microgram/ml. This activity was similar to that of primaquine. In rat therapy models, the WRAIR compounds affected Pneumocyst...

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Bibliografiska uppgifter
Huvudupphovsmän: Bartlett, M S, Queener, S F, Tidwell, R R, Milhous, W K, Berman, J D, Ellis, W Y, Smith, J W
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1991
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC244991/
https://ncbi.nlm.nih.gov/pubmed/2024961
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