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In vitro inactivation of aminoglycosides by sulbactam, other beta-lactams, and sulbactam-beta-lactam combinations.

At clinically achievable levels (e.g., 25 micrograms/ml), sulbactam exerted no effect on aminoglycoside concentrations when incubated together in pooled serum at 37 degrees C for up to 24 h. Sulbactam alone and in combination with ampicillin or cefoperazone inactivated tobramycin, gentamicin, netilm...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Fuchs, P C, Stickel, S, Anderson, P H, Barry, A L, Shilling, S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2014975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.1.182
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