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Impact of dosage schedule on the efficacy of gentamicin, tobramycin, or amikacin in an experimental model of Serratia marcescens endocarditis: in vitro-in vivo correlation.

Aminoglycosides are usually considered to be concentration-dependent antibiotics and to have similar pharmacodynamic and pharmacokinetic properties. To verify the equivalent activity of the aminoglycosides on a susceptible strain, we tested the killing rate of three aminoglycosides (gentamicin, tobr...

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Autors principals: Potel, G, Caillon, J, Fantin, B, Raza, J, Le Gallou, F, Lepage, J Y, Le Conte, P, Bugnon, D, Baron, D, Drugeon, H
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC244950/
https://ncbi.nlm.nih.gov/pubmed/2014965
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