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Structure-activity study of inhibition of amphotericin B (Fungizone) binding to sterols, toxicity to cells, and lethality to mice by esters of sucrose.

The effects of four monoesters of sucrose with different acyl chain lengths (palmitate, C16; myristate, C14; laurate, C12; and caprate, C10) on the aggregation state of amphotericin B (AmB), its binding to cholesterol and ergosterol, its toxicity to cells, and its lethality to mice were determined....

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Библиографические подробности
Главные авторы: Gruda, I, Milette, D, Brother, M, Kobayashi, G S, Medoff, G, Brajtburg, J
Формат: Artigo
Язык:Inglês
Опубликовано: 1991
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC244936/
https://ncbi.nlm.nih.gov/pubmed/2014979
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